Abstract

PHARMACEUTICAL DEVELOPMENT AND STANDARDIZATION OF ASRAHARARISHTA

Dr. Usha Rao N.* and Dr. Vikram S.

.

Abstract

Of all the dosage forms, Sandhana Kalpana are widely used therapeutically as they contain self-generated alcohol which acts as a preservative and this also helps in faster absorption and action of the drug. It stimulates the digestive enzymes thereby increasing the bio availability & therapeutic efficacy of the drug.[1] Asrahararishta[2] is unique Sandhana Kalpana mentioned in Bhaishjaya Ratnavali, Rajayakshma chikitsa prakarana. It is prepared by subjecting fermentation of Mritasanjeevini Sura and Vishalyakarni Swarasa for a duration of 7 days. It is named Asrahararishta since it is used in bleeding disorders to arrest bleeding. which is indicated in Kasa, Rajayakshma, Urakshata, Dhatukshaya, Raktapitta, Raktatisara, Raktapradara. It also has a unique dosage of 10 Bindu, every Yama with Sheetajala as Anupana. As no studies were done on this unique formulation and due to non- availability of this in the market, pharmaceutical development and standardization of Asrahararishta was chosen with an intent to make a valuable contribution in the field and to develop knowledge on the same.

Keywords: Asrahrarishta, Mritasanjeevini Sura, Sandhana Kalpana, Distillation.