Abstract

COMPARATIVE STUDY ON PHYTOCHEMICAL & PHARMACOLOGICAL ACTIVITIES OF CROTON BONPLANDIANUM EXTRACTS OF LEAVES, STEM, SEEDS, AERIAL PARTS & ROOT

Raga Sudha Tayya*

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Abstract

Croton bonplandianum, a member of the Euphorbiaceae family, is a widely distributed plant known for its diverse medicinal properties. The plant has gained scientific interest due to its rich phytochemical composition, which includes flavonoids, alkaloids, tannins, saponins, and terpenoids. This review aims to provide a comprehensive summary of the phytochemical constituents and pharmacological activities of Croton bonplandianum, emphasizing its antimicrobial, antioxidant, anti-inflammatory, anticancer, and hepatoprotective effects. The plant's aerial parts and roots have been found to contain a diverse array of bioactive compounds, including diterpenes, alkaloids, flavonoids, saponins, and phenolic compounds, which contribute to its therapeutic effects. The phytochemical analysis and pharmacological properties of the leaves, stem, root, seeds, and aerial parts are compared to provide a holistic understanding of the plant‟s therapeutic potential. The findings suggest varying concentrations of active compounds and differing bioactivities in different plant parts which may influence their medicinal application. However, the study encourage further study in pharmacological activities in root extracts as they were found to be more significance in antimicrobial and anti-inflammatory activities on comparison with leaves and aerial parts.

Keywords: Croton bonplandianum, phytochemistry, pharmacology, medicinal plants, bioactive compounds, comparative study, leaves, stem, root, seeds, aerial parts.