Abstract

PHYTOCHEMICAL ANALYSIS AND CYTOTOXICITY ASSESSMENT OF LEAF EXTRACTS FROM BARLERIA LONGIFLORA AGAINST ARTEMIA SALINA

R. Sangavi, K. Shri Mathi and S. Premalatha*

Abstract

To investigate the phytochemical profile and cytotoxicity effect, Barleria longiflora leaf extracts obtained using the soxhlet extraction. The phytochemical constituents present in B. longiflora leaf extracts were confirmed by qualitative analysis shows the presence of alkaloids, flavonoids, tannin, steroids, glycosides and triterpenoids were present in various leaf extracts. Ethanol extract of leaf responded for good cytotoxicity properties against Artemia salina. The results revealed that the ethanolic extract of B. longiflora exhibited the highest mortality rate 93% (LC- 18.63) at 1000 ppm concentration. As the concentration decreases the mortality % also decreased. The present study on preliminary phytochemical analysis and cyto-toxicity properties of plant Barleria longiflora contributes to a greater knowledge of this under studied medicinal plant.

Keywords: Barleria longiflora, Qualitative analysis, Artemia salina and cytotoxicity.