Abstract

THERAPEUTIC POTENTIAL OF FLEXINECK SOFT GEL CAPSULES: A GC-MS BASED EVALUATION OF BIOACTIVE COMPOUNDS

Sibi Narayanan*, Bijeshmon P. P., Anusree N. M. and Reeshma C. R.

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Abstract

Cervical spondylosis is a degenerative condition affecting the cervical spine, intervertebral discs, and vertebrae, resulting in pain, stiffness, and neurological symptoms. Conventional treatments, such as NSAIDs, muscle relaxants, and corticosteroids, carry long-term adverse effects, highlighting the need for alternative therapeutic options. Flexineck soft gel capsules, developed by Sitaram Ayurveda, offer a herbal remedy for cervical spondylosis and related musculoskeletal disorders. This study utilizes Gas Chromatography- Mass Spectrometry (GC- MS) to analyze the bioactive compounds in Flexineck, identifying key phytochemicals with anti-inflammatory, analgesic, and antiarthritic properties. The presence of β- Caryophyllene, γ- Sitosterol, and other active constituents suggests potential efficacy in managing cervical spondylosis. These compounds exhibit significant anti-inflammatory, analgesic, antiarthritic, and antinociceptive effects, contributing to symptom relief. This research highlights Flexineck’s therapeutic potential as a natural alternative to conventional treatments and underscores the role of GC-MS in validating the efficacy and safety of herbal formulations.

Keywords: Cervical spondylosis, GCMS, Flexineck, Anti-inflammatory.