Abstract

A POSSIBLE MODELLING OF PARAMETERS INTERACTION OF ENVIRONMENT IMPACT AND HEALTH

Dr. Mohemid M Al-Jebouri*

Abstract

Microbial pathogens include bacteria, viruses, fungi, and parasites and together account for a significant percentage of acute and chronic human diseases. In addition to understanding the mechanisms by which various pathogens cause human disease, research in microbial pathogenesis also addresses mechanisms of antimicrobial resistance and the development of new antimicrobial agents and vaccines. Answering fundamental questions regarding host-microbe interactions requires an interdisciplinary approach, including microbiology, genomics, informatics, molecular and cellular biology, biochemistry, immunology, and epidemiology. erplay between host and microbe. Studies investigated the direct effects of pollutants on respiratory tract infections are very vast, but those interested in the role of a preexisting disease and effects of the exposure on the response to secondary stresses are few. In an experimental study at concentrations of air pollutants found in urban environments, frank toxicological responses are rarely observed; however, exposure to a secondary stress like respiratory challenge with infectious bacteria can exacerbate the response of the experimental host.

Keywords: Microbial pathogens, antimicrobial agents and vaccines, epidemiology.