Abstract

FORMULATION AND EVALUATION OF NICOTINE MUCOADHESIVE TABLET FOR SMOKING CESSATION

Komal Pandit*, Shivani Pangarkar, Kalyani Patange, Pratiksha Patange, Sharayu Patange, Karan Patkar, Vaibhavi Deshmukh

Abstract

One of the main antecedents of cancer, respiratory conditions, and cardiovascular conditions is smoking. Indeed however smoking is truly common or garden Throughout the world, smokers are constantly overpassed and don’t allow helpful brace to stop. Operative treatment is demanded to support smokers in quitting in order to palliate this public health burden. Nicotine relief remedy with gradual abating of nicotine is one of the smoking conclusion styles. Mucoadhesive phrasings are among the new drug delivery systems that are available in the form of tablets and films, and can be used for NRT. Mucoadhesive nicotine tablets when placed in the upper slush will attach to the buccal mucosa and release nicotine content in a controlled manner. This will meet the immediate and long- term need of the individual to the nicotine, analogous that the person can drop his/ her reliance on smoking. One system of delivering nicotine into the bloodstream without smoking is relief treatment. Numerous smoking conclusion capsule forms have increased quitting rates, which has had a major positive impact on public health. The benefit of nicotine buccal mucoadhesive capsule forms for quitting smoking is their high absorption and lack of smelling demand. Significance of smoking conclusion programme on nicotine dependence, oral health, physiological And biochemical parameters among adult smoking stoners at named. His study examines an innovative strategy for quitting smoking, emphasizing the value of learning how to stop rather than actually stopping. The study’s pretensions were fulfilled in a number of stages, including a review of material literature and the development of a suitable theoretical frame, upon which the program's content was established and perfected with the help of subject- matter experts.

Keywords: Mucoadhesive tablet, nicotine, smoking cessation.