Abstract

POLYHERBAL TOPICAL GEL FOR THE TREATMENT OF ACNE

Suruchi Ghusalkar*, Sonali Rashinkar, Anjali Pathekar, Snehal Hosurkar and Alim Shaikh

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Abstract

The skin is the most vulnerable element of the body. Acne, pimples, pigmentation, and sunburn markings are common skin issues caused by daily exposure. Acne is the most frequent skin disorder nowadays. Acne vulgaris is a follicular skin condition that affects the Pilosebaceous unit of the face, neck, and trunk. It causes inflammatory (papules, pustules, nodules, and cysts), non- inflammatory (seborrhoea and comedones), and scarring. Acne is primarily caused by Propionibacterium acnes (P. acnes), which causes inflammation by releasing extracellular enzymes such as proteases, hyaluronidase, and lipases. Acne, black spots, and other skin problems affect 90-95% of the pubertal population, 25-45% of adults, and less than 25% of women. Women above the age of 25 can still experience adult female acne. Acne vulgaris has traditionally been treated with topical and systematic therapy containing synthetic chemicals. Herbal medicines offer a safer and more effective alternative to synthetic pharmaceuticals for treating acne vulgaris. Natural remedies for acne vulgaris have gained popularity due to their efficiency in treating the disfiguring condition.

Keywords: Acne vulgaris, Propionibacterium acnes, Herbs, Antibacterial, Anti-inflammatory.