Abstract

TREATMENT WITH GLP-1 RECEPTOR AGONISTS AND IMPACT ON QUALITY OF LIFE

Nikolay Kostadinov* and Tcvetelina Totomirova

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Abstract

Diabetes mellitus is among the four most common chronic diseases in Bulgaria. Its impact on affected individuals seriously reduces the quality of life in physical, psychological and social aspects. Patients often have to adhere to strict diets and take regular medications. This can lead to feelings of limitation and stress that affect an individual's quality of life. The concept of quality of life makes it possible to address and satisfy all the individual physical and mental health needs of patients. Quality of life is generally defined as a subjective sense of well-being that is influenced by various factors. The object of the present study is the quality of life of patients with type 2 diabetes mellitus treated with GLP-1 receptor agonists and how these medications affect various aspects of quality of life. The aim of the present analysis is to investigate the quality of life of patients with type 2 diabetes mellitus treated with GLP-1 receptor agonists and how the latter affects different aspects of quality of life. A total of 66 patients treated with a GLP-1 receptor agonist were studied, whose quality of life was assessed using the SF-36 and ADDQoL questionnaires. Quality-of-life factors were identified, including characteristics related to the type of treatment given and the group of GLP-1 receptor agonists used.

Keywords: type-2 diabetes mellitus, GLP-1 receptor agonists, quality of life.