Abstract

ADVANCED MICROSPHERE TECHNOLOGY: TRANSFORMING CONTROLLED DRUG RELEASE

Lokesh M.* and Bhuvaneshwari M.

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Abstract

Currently, an effective drug delivery carrier is needed to deliver therapeutic compounds to the target site. This carrier can administer the medication consistently and carefully just at the site of action. Microspheres are one of several such carriers that meet all the requirements for a powerful drug carrier. Microspheres are characterized as free-flowing, spherically shaped particles. Composed of proteins or artificial polymers that are either biodegradable or nonbiodegradable and, ideally, have a particle size between 1 and 1000 μm. By overcoming the drawbacks of traditional dose forms, this innovative drug delivery technology seeks to improve patient compliance, boost bioavailability, and administer medications or other active substances more precisely.The best features, kinds, preparation techniques, assessment of their qualities, in vitro-in vivo correlation, and uses of microspheres as drug carriers are all covered in this review article. Today, there are numerous techniques for creating microspheres that aim to achieve consistency, repeatability, and high entrapment efficiency.

Keywords: Microspheres, Drugdelivery, Targetedtherapy, Controlledrelease, Bioavailability, encpsulation efficiency, preparation, Application.