Abstract

ANTI BACTERIAL ACTIVITY AND ANTI DIABETIC ACTIVITY OF PLANT SZYGIUM ALTERNIFOLIUM AND THEIR PHYTOCHEMICAL CONSTITUENTS

Dr. P. Vasanth Kumar*, T. Afreen, S. Abrar Ahamed and S. Nadiya Apseen, B. Nandini, B. Nirosha, S. Chandana, G. Sruthi Chandana, K. Nikitha and T. Venkatesh

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Abstract

The antibacterial properties of Syzygium alternifolium, a medicinal plant native to various parts of Asia, have gained interest in recent years. This review explores the antibacterial potential of the plant, its bioactive components, and the methods used to evaluate its efficacy against bacterial pathogens. Findings from multiple studies highlight its promising role in combating bacterial infections, particularly against resistant strains. The paper also discusses the challenges and future perspectives of using S. alternifolium as an alternative or adjunctive therapy. Diabetes, characterized by hyperglycemia, is one of the most significant metabolic diseases, reaching alarming pandemic proportions. It can be due to the defects in insulin action, or secretion, or both. The global prevalence of diabetes is estimated at 425 million people in 2017, and expected to rise to 629 million by 2045 due to an increasing trend of unhealthy lifestyles, physical inactivity, and obesity. Several treatment options are available to diabetics, however, some of the antidiabetic drugs result in adverse side effects such as hypoglycemia. Hence, there has been a proliferation of studies on natural products with antidiabetic effects, including plants from the Myrtaceae family, such as Psidium guajava Eucalyptus globulus, Campomanesia xanthocarpa, and more significantly, Syzygium sp. Previous studies have shown that a number of Syzygium species had potent antidiabetic effects and were safe for consumption. This review aims to discuss the antidiabetic potential of Syzygium sp., based on in vitro and in vivo evidence.

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