Abstract

PREPARATION AND ANALYTICAL STUDY OF PANCHPALLAV KWATHA GRANULES TO EVALUATE THEIR ANTIMICROBIAL ACTIVITY(IN-VITRO)

*Dr. Maithili Anil Kurwade, Dr. Sheela Pargunde

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Abstract

Ayurveda deals with various formulations with respect to various dosage form Oral hygiene is most important in health Panchapallava Kwatha is a formulation mentioned in Chakradatta, Bhaisajya ratnavali. For mouth wash. In order to become granular, Panchapallava kwatha, a traditional Ayurvedic formulation known for its medicinal properties in Mukha Dhawan (oral health), underwent pharmaceutical processing and analysis. The objective of this study was to optimize the formulation while maintaining its conventional therapeutic characteristics in order to improve convenience, efficacy, and stability. The manufacturing method for Panchapallava kwatha started with the extraction of bioactive substances from its botanical elements. Next, using contemporary pharmaceutical techniques, the mixture was formed into granules. The granules underwent a thorough evaluation process to assess their physical attributes and their compliance with Ayurvedic pharmacopeial criteria by analytical study. analytical investigation employing tests that are indicative of their potential and efficacy, such as pH, alcohol soluble extractive, water soluble extraction, moisture content, total ash, and acid insoluble ash. Analytical study demonstrated that the granules are free from adulteration, contamination, ensuring their safety. In addition, the granular formulation showed better solubility than the conventional decoction form, which could increase therapeutic results and patient compliance. The goal of the project is to create novel dosage forms that satisfy safety and efficacy requirements. To sum up, the granular form of Panchapallava kwatha is a noteworthy development in Ayurvedic medicine and gives a viable treatment option for Mukha Dhawan.

Keywords: Panchpallav Kwatha, Panchapallav kwatha granules, oral hygiene.