Abstract

EVALUATION OF ANTI-ANXIETY ACTIVITY OF FICUS RACEMOSA FRUIT ON MICE

*Mr. Ganesh Tukaram Lokewar, Miss. Fiza Pathan Y., Dr. Wadulkar R. D., Dr. Kranti Satpute

Abstract

Anxiety disorders are increasingly being recognized as a global problem affecting all age groups, which are characterized by a variety of neuroendocrine, neurotransmitter, and neuroanatomical disruptions. Anxiolytic drugs have higher effect sizes than psychosocial therapies and show effect in a shorter time; however, they have an unfavourable risk/benefit ratio, as they produce anterograde amnesia, dependence, abstinence syndrome, paradoxical reactions in humans, and decay of psychomotor functions. The present investigations validate the traditional use of Ficus racemosa fruit as nerve soother, and conclude that the fruit has great potential for being developed as an effective antianxiety agent.

Keywords: Ficus racemosa, EEFR (ethanolic extract of ficus racemosa), EPM (Electronic plus maze model).