Abstract

PREPARATIONS AND EVALUATION ASHWAGANDHA CAPSULE FOR ANTIARRHYTHMIC PROPERTIES

Neha Rathod*, Pranali Ambilwade, Vaishnavi Jakhad, Jayashri Chavan, Navnath Chavan and Satyapal Chavan

Abstract

Among the most prevalent heart conditions is arrhythmia. The search for new drugs to suppress various heart diseases is always of great interest. In the last decade, there has been a lot of attention in the investigation of potent antiarrhythmic substances from plants. These natural compounds exhibit antiarrhythmic effects and chemical modifications on natural compounds have greatly increased their therapeutic properties. Herbal antiarrhythmic medication chemical modification is directly linked to new drug development and marketing. Thus, this study will discuss the structural characteristics and mechanisms of natural compounds' action that have antiarrhythmic activities so that chemists can select the primary antiarrhythmic compounds. from natural compounds. on the target of the disease - chemical structures. Coordinated ion channel and transporter activity is necessary for the well-ordered transmission of electrical impulses across the heart and the maintenance of a regular cardiac rhythm. The presence of structural cardiac disease resulting from myocardial infarction (owing to fibrotic scar development) or left ventricular dysfunction significantly increases the risk of common acquired arrhythmias.

Keywords: Arrhythmia, Cardiovascular, Myocardial infraction, Fibrotic scar.