Abstract

EVALUATION OF CLINICAL OUTCOMES OF FLUTICASONE FUROATE VS FLUTICASONE PROPIONATE NASAL SPRAYS IN ALLERGIC RHINITIS – A PROSPECTIVE STUDY

Dr. Aakaram Sujala*, Gauri Diggikar, Konduru Bhuvaneshwari, Venreddy Madhuhasini Reddy, Dr. Ashok Prudviraju Moganti, Sreemantula Divya and Dr. Tirunagari Mamatha

Abstract

Allergic rhinitis (AR) is an atopic disease characterized by symptoms of nasal congestion, clear rhinorrhoea, sneezing, postnasal drip, and nasal pruritis. The aim and objective of the study to compare the effects of these two nasal sprays on symptom relief and quality of life for patients suffering from allergic rhinitis. Fluticasone furoate and fluticasone propionate are both commonly used corticosteroids for the management of allergic rhinitis. The study was desigined a prospective study, the population of the study are 60 cases of allergic rhinitis and patients with mild-to-severe allergic rhinitis were selected for the study. They were randomly divided into two groups; group I consists of 30 patients who received intranasal Fluticasone Furoate nasal spray, total daily dose of 27.5g (110mcg) as 2 puffs in each nostril administered once daily, whereas the group II consists of 30 patients who received Fluticasone propionate nasal spray, total daily dose of 50 mcg as 2 puffs in each nostril administered twice daily. The conclusion of the study was Analysis on patient-based symptoms revealed that both the groups showed statistically significant reduction in symptoms.

Keywords: Allergic rhinitis, Fluticasone propionate, 2 puffs and Fluticasone furoate.