Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL ANALYSIS OF PUNARNAVA MANDURA -AN AYURVEDIC HERBOMINERAL FORMULATION FOR ANEMIA ASSOCIATED WITH NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE (NDD- CKD) (KAPHAJA PANDU)

Seema Kushwaha*, Mandip Goyal and Harisha C. R.

.

Abstract

Background: Punarnava Mandura is mentioned by Acharya Charaka as a drug for the management of Pandu and Sotha. So for initialization of standardization and assurance of the quality of herbal compounds pharmacognostical and pharmaceutical analysis should be done. Methods: Punarnava Mandura was subjected to microscopic evaluation for pharmacognostical and physicochemical analysis like Loss on drying, total ash, water soluble extract, alcohol soluble extract and ph value. Results: Pharmacognostical study showed the presence of certain identifying characters of all the ingredients of Punarnava mandura like Punarnva, Trikatu, Triphala, Vidanga, Kushtha, Devdaru, Trivruta, Haridra, Chavya, Daruharidra etc. As per the preliminary physiochemical analysis, loss on drying percentage of the Punarnava Mandura was 2.67 % w/w, pH value was 6, total ash value was 68.7 % w/w, Water soluble extractive was 23%w/w and Methanolsoluble extractive was 12.6 w/w. Conclusions: Pharmacognostical and physico-chemical observations revealed the specific characteristics of all active constituents of Punarnava mandura confirmed the purity and genuinity of the drug.

Keywords: Punarnava mandura, Anemia associated with NDD -CKD, Kaphaja Pandu, Pharmacognosy, Pharmaceutical analysis.