Abstract

KARAVEERA IN THE LIGHT OF AGADATANTRA (TOXICOLOGY) - A REVIEW ARTICLE

Ajay Kumar* and Jai Kumar Singh

Abstract

Karaveera, although considered an Upavisa (Potentially toxic substance), has been a part of Ayurvedic medicine for treating various diseases. The different parts of Karaveera and its various dosage forms have been employed in both external and internal applications to address numerous health conditions. Pita Karaveera (Thevetia peruviana) is a medicinal plant known for its wide range of pharmacological properties, but it has not received significant scientific attention. Classical texts on Ayurveda were written over different periods since the field's inception. Unfortunately, this information has not been critically reviewed or published in a comprehensive format. Therefore, a systematic review concerning the identification and use of this classical drug is essential. The plant contains active compounds like cardiac glycosides, particularly peruvoside, which have been well-studied. Its bark tincture is used for malarial fever and snakebites, while macerated leaves and bark treat amenorrhea. A decoction of leaves helps with jaundice, fever, and intestinal worms. Karaveera is classified in classical Ayurveda by its synonyms, varieties, group, tastes, actions, and therapeutic uses, primarily for treating Kustha (Leprosy). More research is essential to explore its medicinal value for mankind. Suicide is common amongst village women, the use of it as a paste or decoction. So, it is also important in forensic medicine.

Keywords: Ashvamara, External uses, Internal uses, Nerium oleander, Poisons, Thevetia peruviana, Upavis, Medico-legal, Toxic, Postmortem.