Abstract

FORMULATION AND EVALUATION OF AN ANTIFUNGAL PAPER STRIP

Mr. Shubham Shirsath*, Mr. Kshitij Varma, Mr. Bhushan Shirsath, Mr. Rushikesh Sonawane, Mr. Vedant Sonawane, Miss Siddhi Sonawane, Miss Sapana Sonawane

Abstract

In recent years, fungal infections have become an increasingly significant global health concern. This rise in prevalence is partly due to the growing number of immunocompromised patients, the widespread use of antimicrobial, and environmental changes that promote fungal proliferation. Fungal pathogens, such as Candida, Aspergillus, and Trichophyton, are responsible for a wide range of infections, including superficial skin conditions, systemic infections, and mucosal infections. Traditional treatment approaches often face limitations due to issues like poor bioavailability, drug resistance, and side effects associated with oral or systemic antifungal agents. Therefore, there is a growing demand for innovative drug delivery systems that can improve the efficacy of antifungal treatments while minimizing these issues. One promising strategy is the use of novel drug delivery systems that not only improve the localized delivery of antifungal agents but also ensure sustained and controlled release to enhance therapeutic outcomes. In this context, the development of a paper strip-based antifungal dosage form has been explored as an effective alternative to conventional dosage forms such as creams, ointments, or oral tablets.

Keywords: Stone flower, Pharmacological profile, phytochemical aspects, phytoconstituent.