Abstract

NANO-LIPID CARRIERS: A PROMISING APPROACH TO ENHANCING SUNSCREEN EFFICACY AND SKIN PROTECTION

Anupriya Yadav, Iti Chauhan* and Bhawna Sharma

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Abstract

Background: Sunscreens protect the skin from UV radiation, which can cause damage and skin cancer. However, typical sunscreen formulations have drawbacks such as low stability, uneven distribution, and poor skin retention. Nano-lipid carriers (NLCs) are a promising approach for increasing the transport and efficacy of sunscreen chemicals. NLCs, which are made up of solid lipid nanoparticles (SLNs) and nanostructured lipid carriers, can encapsulate both hydrophilic and lipophilic UV filters, resulting in improved skin penetration and longer-lasting protection. Objective: This study aims to assess how NLCs can enhance sunscreen efficacy, skin protection, and user comfort by improving UV filter stability, controlled release, and retention while minimizing irritation and photodegradation. Methods: A comprehensive literature search was conducted across several databases, including PubMed, Wikipedia, Academia, and Google Scholar. The search utilized a variety of key terms such as Nano-Lipid Carriers, UV, Sunscreen efficacy, skin protection, Nanocarriers, Nano-lipid carriers, Topical drug delivery, Solid-lipid nanoparticle, Liposomes, Nanoemulsions, Nanocarriers for sunscreen, Improved SPF, UVB protection, UVA protection, UV-blocking agents, absorber, UV reflectors and Photostability The focus of the search was specifically on Nano-Lipid Carriers as a promising approach to enhancing sunscreen efficacy and skin protection. Studies related to Nanostructured lipid carriers or sunscreen agents were excluded from the review. Results: NLC-based sunscreens demonstrated increased stability, controlled release of active ingredients, and enhanced photoprotection. They improved skin penetration and retention while also providing antioxidant and anti inflammatory properties. The formulations also caused minor skin irritation. Conclusion: I n conclusion, NLCs improve sunscreen efficacy by enhancing sta bility, controlled release, and skin protection, paving the way for more effective and skin friendly formulations.

Keywords: Nan o lipid carriers, skin, UV rays enhancing stability, SPF, sol i d lipid nanoparticle, skin protection bioavailability.