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Abstract

RECENT OVERVIEW: NANOFORMULATION

Samruddhi V. Deokate*

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Abstract

Nanoformulation development is the design and manufacture of nanoscale materials, typically ranging from 1 to 100 nanometers, with the goal of increasing the efficacy, stability, and bioavailability of pharmaceutical, cosmetic, and agricultural goods. This developing discipline uses nanoparticles' unique qualities, such as expanded surface area, greater solubility, and the capacity to target specific cells or tissues, to overcome the limitations associated with traditional formulations. In the pharmaceutical industry, nanoformulations enable the delivery of poorly water-soluble drugs, increase their bioavailability, and reduce side effects by facilitating controlled or sustained release. Techniques such as nanoparticle encapsulation, lipid-based carriers, and polymeric micelles are commonly used to enhance the delivery and therapeutic potential of active ingredients. These technologies can also improve the pharmacokinetics and pharmacodynamics of drugs, leading to more effective treatments. In cosmetics, nanoformulations enhance the penetration and stability of active ingredients like vitamins, antioxidants, and peptides, improving skin absorption and therapeutic outcomes. Similarly, in agriculture, nanoscale formulations can improve the delivery of pesticides and fertilizers, reducing environmental impact and increasing crop yield. Despite the promising potential, the development of nanoformulations presents challenges, including scalability, regulatory concerns, and safety considerations. Therefore, continued research into the design, testing, and regulation of nanoformulations is crucial to ensure their safe and effective application across various industries.

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