Abstract

DEVELOPMENT AND STANDARDIZATION OF AN AYURVEDIC HERBAL EYE DROPS FOR DRY EYE SYNDROME

N. Srikanth, A. Singh*, S. Pawar, S. N. Murthy, R. R. Padmavar

Abstract

Ayurvedic literatures recount potential ophthalmicdrugs for the management of surface inflammatory conditions of eye such as dry eye syndrome(DES) or Keratoconjunctivitis Sic ca(KCS). The plant drugs such as Berberi saristata DC. and Glyeyrrhiza glabra Linn. are attributed with potential anti-inflammatory, anti-allergic and wound healing activities backed by scientific evidences. With this rationale and background, an Ayurvedic eye drops was developed for dry eye syndrome (DES) systematically following contemporary methods and parameters right from quality assurance of ingredients, formulation of standard operation procedures (SoPs) and also complying to the quality and safety standards of finished product for ophthalmic preparation as specified in Indian Pharmacopeia. The pre-clinical ocular toxicity studies also revealed safety of this formulation on topical use.

Keywords: eye drops, dry eye syndrome, Standardization, TLC.