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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

FORMULATION AND EVALUATION OF POLYHERBAL EYE PATCH

Maria Peter, Josna Jose and Anupriya Mahesh*

Abstract

The purpose of present study is to formulate and evaluate Polyherbal eye patch. Dark circles under the eyes are bilateral, homogeneous pigment macules on the infraorbital regions. Due to their ability to precisely administer active ingredients to the sensitive under eye region, under-eye gel patches are utilized as both cosmetics and cosmeceutical. The Polyherbal under eye patch is prepared by using natural ingredients like Aloe Vera, Honey, Neem, and Coconut Oil with gelling agents like Carbopol 934, PVA, and Gelatin. Gel base is prepared by using Carbopol 934, PVA, and Gelatin. By changing the ingredients and their concentration we formulated 4 different formulations namely F1 to F4. The herbal under eye patch was evaluated by different parameters such as Organoleptic evaluation, pH test, homogeneity, DPPH test, spreadability, thickness, peel test, stability study, viscosity, swelling index and phase separation were observed. After the evaluation, we found good properties for the eye patch (Formulation1, F1) and maintained its consistency even after stability storage conditions. The DPPH study result also a supporting document for the antioxidant activity of our extract, the activity increases as the quantity of extract increases. The eye patches were to be stable during stability studies according to ICH guidelines. It can be concluded that herbal eye patch without side effects having anti-oxidant property having enough potential to give a barrier to protect the skin and avoid aging of skin. The overall study is useful to substantiate product claims due to its useful benefits on antiwrinkling activity.

Keywords: Polyherbal under eye patch; Dark Circles; Aloe Vera; Honey; Neem; Carbopol934; PVA; Gelatine; Coconut Oil And Anti-Wrinkling Activity.


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