Abstract

ANTHELMINTIC ACTIVITY OF SELECTED MEDICINAL PLANTS

M. Priyanka*, Dr. R. Manivannan, B. Gokulakannan, P. Gunal, P. Jeeva,

Abstract

Helminthic infections remain a significant global health concern, particularly in developing regions. Synthetic anthelmintic drugs have provided effective treatment, but increasing drug resistance calls for newalternatives. This article explores the anthelmintic potential of various medicinal plants, highlighting their traditional use, bioactive constituents, and mechanisms of action, supported by contemporary research. Helminth infections remain a major public health issue, especially in developing countries, contributing to malnutrition, anemia, and general debilitation. The growing resistance to conventional anthelmintic drugs has driven interest in exploring alternative therapies, particularly those derived from medicinal plants. This study evaluates the anthelmintic activity of selected medicinal plants traditionally used in folk medicine. Methanolic and aqueous extracts of [insert plant names] were screened for their efficacy against Pheretima posthuma and Ascaridia galli using standard in vitro models. Parameters such as time to paralysis and death were recorded and compared with a standard reference drug (Albendazole). The results indicated that [mention the most effective plant] exhibited significant dose-dependent anthelmintic activity, comparable to the standard drug. Phytochemical analysis revealed the presence of compounds such as tannins, alkaloids, and flavonoids, which may contribute to the observed bioactivity. These findings support the traditional use of these plants and highlight their potential as sources of novel anthelmintic agents.

Keywords: .