Abstract

VITAMIN B6 DEFICIENCY AND ITS LONG TERMS EFFECTS ON PATIENTS WITH LIVER DISEASES

*Krishna Rajesh Chhoda, Saurabh Tanaji Shinde, Jay Ravindra Sutar, Akash Chandrakant Tolanur, Dr. Sudarshan Narayan Nagrale, Dr. Vishal Bharat Babar

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Abstract

The liver is a important gland in the body and play role in the body functions such as blood clotting and various metabolism. Most people are taking illnesses substances which cause liver damage. Liver disease is defined as acute or chronic liver on the basis of whether the history of disease is less than or greater than 6 months respectively and disturbance of liver functions that causes liver damage. The various liver diseases have various sign symptoms and causes. The mainly liver cirrhosis is irreversible disease. In cirrhosis replacement of liver tissue by fibrosis, scar tissue and regenerate nodules causes loss of liver function. The etiological of which involves Alcohol consumption, Hepatitis A, B and C, Non alcoholic fatty liver disease and Primary Biliary Cholangitis. History and physical exam, laboratory test and imaging test are the diagnosis test of cirrhosis. Vitamin B6 is a water soluble Vitamin. There are three different natural form of vitamins b6 pyridoxine, pyridoxamine and pyridoxal which normally present in foods. Humans are depend on external sources to cover their vitamin B6 requirements and the pyridoxal 5 – phosphate (PLP) form is of major importance.

Keywords: liver disease, vitamin B6 deficiency, cirrhosis, amino acid metabolism.