Abstract

A PROSPECTIVE OBSERVATIONAL STUDY TO ASSESS THE PREVALENCE AND IMPACT OF MEDICATION ADHERENCE IN CHRONIC KIDNEY DISEASE PATIENTS WITH OR WITHOUT COMORBIDITIES IN A TERTIARY CARE TEACHING HOSPITAL

Manasa T., J. S.Venkatesh, P. Yadunandan Yadav, Riya Rajan, Sandra Joemol Koshy and Sandwana Sunil*

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Abstract

Chronic kidney disease (CKD) is a long standing disease of the kidneys leading to renal failure. Medication adherence is the major factor that determines the therapeutic outcomes in the patient which in turn improves the quality of life. To study the prevalence of CKD related variables and to assess the Medication Adherence using Morisky Medication Adherence Scale (MMAS-8) questionnaire. A prospective observational study was conducted in 180 patients for a period of 6 months in the inpatient general medicine department who were diagnosed with CKD. A total of 180 questionnaires was reviewed and analysed. 180 patients were enrolled in the study, with the prevalence being 61% male and 39% female. Majority of the participants (27.2%) were aged between 51-60 years. Among the total population, 110 patients belonged to stage V, and 79 patients were undergoing haemodialysis. Swelling was the most prevalent symptom observed in patients with CKD. Hypertension, followed by DM, CVD was the most observed comorbidity. According to the MMAS-8 scale, high, moderate, low adherence was reported in 35%, 42%, 22% respectively. Out of the total, 67 patients were classified as adherent population. Gender-wise adherence was seen 24% males and 13% females. Disease adherence and non-adherence was most prominent among CKD patients. In this study, Furosemide was the commonly prescribed medication to 80% of the patients. The prevalence of CKD related variables revealed a remarkably high incidence of medication non adherence among patients with CKD.

Keywords: Chronic kidney disease; Prevalence; Morisky medication adherence scale; Comorbidity; Medication adherence.