Abstract

SYNTHESIS OF SILVER NANOPARTICALS FROM AEGLE MARMELOS LEAF EXTRACT BY GREEN SYNTHESIS APPROACH AND PREPARATION AND EVALUATION OF ANTIMICROBIAL CREAM. – A REVIEW

Shinde Supriya V.*, Shevate Ankita Sunil, Kadam Sanika Santosh, Shelar Shreya

Abstract

Nanoparticles are novel drug delivery systems. They have tremendous advantages over the conventional drug delivery system. Hence, these days researchers been working on finding out optimal usage of silver nanoparticles in various fields including medicine. Silver nanoparticles are one of the nanoparticles, which have significant therapeutic applications such as antimicrobial, treat burns, anti inflammatory and immunomodulatory effects. But they have many side effects due to usage of synthetic excipients. To avoid this problem green synthesis approach for synthesis of silver nanoparticles is making a good impact on drug delivery and it’s improved safety. The synthesized nanoparticles are characterized for checking it’s physical and chemical properties by techniques like spectroscopy, transmission electron microscopy, chromatography etc. As well for ease of application of silver nanoparticles for its Antimicrobial properties on skin, topical cream is convenient option. This cream is evaluated by different evaluation tests like morphology, pH, Viscosity, spreadability and it’s antimicrobial activity against different pathogens.

Keywords: Nanotechnology, Nanoparticles, Green synthesis, Silver nanoparticles, Algae Marmelos, Antimicrobial cream.