Abstract

FORMULATION AND EVALUATION OF ANTI- ACNE CREAM FROM FLAX SEED

Mrs. Sonali R. Kote, *Mr. Aditya D. Katkar, Mr. Ashish S. Kumbhakarn and Miss. Gunjan G. Vikhe

Abstract

The present study focuses on the formulation and evaluation of an antiacne cream utilizing flax seed (Linum usitatissimum) extract, known for its rich content of omega-3 fatty acids, lignans, and antioxidants. Acne vulgaris is a common dermatological condition caused primarily by inflammation, bacterial proliferation (particularly Propionibacterium acnes), and excessive sebum production. Natural remedies with minimal side effects have gained increasing attention for acne treatment. In this research, flax seeds were subjected to extraction using a suitable solvent system, and the obtained extract was incorporated into a topical cream base. Various formulations were prepared and evaluated for physicochemical parameters including pH, viscosity, spreadability, stability, and microbial load. The anti-acne potential was assessed through in vitro antibacterial activity against P. acnes and Staphylococcus aureus using the agar well diffusion method. Among the tested formulations, the optimized batch demonstrated excellent consistency, stability, and significant antibacterial activity, indicating the efficacy of flax seed extract in acne treatment. The results suggest that flax seed-based herbal cream could serve as a promising, safe, and cost-effective alternative for the management of acne.

Keywords: Anti acne, Flax seed extraction, Acne treatment.