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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

FORMULATION AND EVALUATION OF ECO-TWIST SEMISOLID MOSQUITO REPELLENT STICKS

*Sayali Prakash Shinde, Komal Tanaji Patekar, Manasi Sanjay Shelar, Pratiksha Bhimrao Sonwalkar

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Abstract

Purpose: The demand for plant-based mosquito repellents has grown due to concerns over the safety and side effects of synthetic agents. This study aimed to formulate and evaluate semi-solid stick preparations using Lantana camara and marigold oils for effective topical mosquito repellency. Method: Five formulations (F1–F5) were developed using stearic acid, cetyl alcohol, and natural oils in varying ratios. The sticks were evaluated for organoleptic characteristics, pH, washability, melting point, skin irritation, and physical stability. The best-performing formulation was selected based on an integrated assessment of these parameters. Results: All formulations exhibited a pleasant odor and yellow to dark-yellow color, with pH values ranging from 4.0 to 5.0 and no evidence of skin irritation. F3 emerged as the optimal formulation, showing a balanced melting point (76–81 °C), smooth non-greasy texture, good washability, and surface integrity. In contrast, F4 and F5 were overly sticky and less washable, while F1 and F2 lacked adequate oil content for long-lasting repellency. Conclusion: Formulation F3 demonstrated the best balance of efficacy, user acceptability, and physical stability, making it a promising candidate for a natural mosquito repellent stick. Further work is warranted to evaluate its repellency duration and performance under field conditions.

Keywords: Mosquito repellent, Lantana camara, marigold oil, semi-solid twist-up stick, herbal formulation.


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