Abstract

LITERATURE REVIEW OF SHILASINDURA WITH SPECIAL REFERENCE TO CLASSICAL AND CURRENT RESEARCH UPDATES

Dr. Ajitkumar Yadav*, Dr. Nalini Hedaoo and Dr. Piyush Gandhi

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Abstract

Shilasindura is a Kupipakva Rasayana formulation containing arsenic (Arsenic disulphide-Manshila), widely utilized in the management of critical diseases such as Shwasa (respiratory disorders), Kasa (cough), and Kushta (skin ailments) in the contemporary era. According to Ayurvedic pharmaceutical principles, Shilasindura is classified as Sagandha (contains sulphur), Sagni (includes heating), and Kanthastha Kupipakva Rasayana (final product accumulates at the neck of the glass bottle). Shodhit Manshila (purified arsenic sulfide) serves as a key ingredient in this formulation. The present study constitutes a comprehensive review of Shilasindura, meticulously compiled from various classical Rasa texts and research articles published across diverse journals, sourced through academic databases. This investigation has systematically documented references to Shilasindura across nine classical Rasa texts and five research publications dedicated to this subject. Furthermore, the study presents detailed insights into Shilasindura's pharmaceutical processing, analytical evaluation, safety profile, and therapeutic efficacy based on available literature and research findings.

Keywords: Shilasindura, Kupipakva, Manshila, Ayurveda.