Abstract

QUALITY ASSESMENT OF KRISHNAAGNYAADI CHURNA: A PHARMACEUTICAL AND PHYTOCHEMICAL EVALUATION THROUGH PHYSICOCHEMICAL ANALYSIS AND HPTLC PROFILING

Dr. Sisira Krishna* and Dr. Sanila V. K.

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Abstract

Introduction: Krishnagnyaadi Churna is a classical herbal formulation mentioned in Sahasrayoga (Churna Prakarana). It is primarily indicated in Sopha (edema/swelling). This study aims to evaluate the pharmaceutical and analytical characteristics of Krishnagnyaadi Churna to establish preliminary standardization data. Materials and Methods: The churna was prepared following traditional guidelines. Analytical parameters such as pH, loss on drying (LOD), water-soluble extractive, total ash, acid-insoluble ash, microbial contamination, and HPTLC fingerprinting were assessed. Results: Pharmaceutical analysis of the formulation yielded the following results: Loss on drying (LOD): 6.42% w/w, pH: 3.55,Total ash: 7.14% w/w, Acid-insoluble ash: 2.40% w/w, Water-soluble extractive: 41.25%w/w, Total bacterial count: 76 CFU/g, Total yeast and mold count: 12 CFU/g.

Keywords: Krishnagnyaadi churna, sopha, pharmaceutical study, analytical parameter, quality control.