Abstract

MODIFIED DOSAGE FORMS OF LEHA KALPANA: A CONTEMPORARY PHARMACEUTICAL PERSPECTIVE ON TRADITIONAL AYURVEDIC SEMISOLID FORMULATIONS

Dr. Rajendra Mane* and Dr. Hemali H. Diwani

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Abstract

Leha Kalpana, a classical semisolid Ayurvedic dosage form, has been used for centuries for its therapeutic benefits, particularly in respiratory and digestive disorders. However, issues such as low bioavailability, instability, and poor palatability have limited its widespread adoption in contemporary medicine. This study explores modified forms of Leha Kalpana, including lozenges, linctuses, herbal jellies, encapsulated forms, and nanoformulations. Lozenges, also referred to as medicated candies or lollies or herbal cough drops, offer several advantages— they begin absorption through the mucosal lining of the mouth, are palatable, easy to administer, and are especially beneficial for children and elderly patients. Compared to the long and labor-intensive preparation process of traditional Leha Kalpana, lozenges are easier and quicker to manufacture with better dosage precision and hygiene control. The research integrates classical Ayurvedic literature with modern pharmaceutical findings. Results indicate that modified forms improve stability, absorption, and patient compliance. These findings suggest a promising future for integrating traditional formulations into mainstream healthcare using modern drug delivery technologies.

Keywords: Leha Kalpana, Ayurveda, modified dosage forms, nano-herbals, lozenges, Rasashastra, pharmaceutical modernization.