Abstract

ENSURING QUALITY AND EFFICACY: PHARMACEUTICOANALYTICAL STANDARDIZATION OF DHATURAPATRADI TAILA

Dr. Jyotirmayee Senapati*, Dr. Kirtesh Agey, Dr. Yagnik Mundadiya, Vd. Dillip Prajapati, Vd. Joban Modha, Prof. Dr. BJ Patgiri

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Abstract

Introduction: Bhaishajya Ratnavali by Acharya Kaviraj Govind Das Sen is the classic which has described Dhaturapatradi Taila in the context of both Shiro Roga Chikitsa and Krumi Roga Chikitsa, the example of Sneha Kalpana (Medicated oleaginous dosage form). Materials and Methods: Classical Sidhdhi Lakshana (Chief desired characteristics) have their certain limitations and are not sufficient to characterize with respect to their organoleptic characters. Thus, in this study three batches of Dhaturapatradi Taila with an average 465 ml of Sarshapa Taila (Mustard oil), 1846 ml of Dhatura Patra Swarasa (Drava dravya) and 57.6 g of Kalka were prepared by the following processes: Sarshapa Taila Murchhana, preparation of Kalka, and Snehapaka with classical method to maintain process uniformity and to evaluate standard procedure. The pharmaceutical and analytical data were observed and recorded. Results: Average total duration for Taila Paka and yield for each batch of Sarshapa Taila Murcchana and Dhaturapatradi Taila were observed to be approximately 7 h 18 min and 460 ml and 6 h 25 min and 371.66 ml, respectively, in 3 days. Average values of physicochemical parameters of Dhaturapatradi Taila were as follows: specific gravity 0.9165, acid value 10.78, saponification value 176.27, and iodine value 109.08 at room temperature. Conclusion: The pharmaceutical and analytical studies have helped to generate preliminary standards for formulation Dhaturapatradi Taila.

Keywords: Dhaturapatradi Taila, standardization, Murcchana, Snehapaka.