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Abstract

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF FIVE MEMBERED CYCLIC IMIDE DERIVATIVES OF MONO, DI AND TRI SUBSTITUTED AROMATIC AMINES AND NAPTHYL AMINE

Ravindra S. Dhivare, and Shankarsing S. Rajput*

Abstract

The five membered cyclic imide derivatives were prepared by reacting succinic anhydride with substituted aromatic amines and napthyl amine to get 3-(N-phenylcarbamoyl) propanoic acid and 3-(Nnapthylcarbamoyl) propanoic acid. These intermediates underwent ring closer with acetyl chloride furnished five membered cyclic imides derivatives. All these derivatives were screened for antimicrobial activities.

Keywords: Heterocycles, 3-(N-phenylcarbamoyl) propanoic acid, 3-(N-napthylcarbamoyl) propanoic acid, cyclic imides, antimicrobial activity.


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