Abstract

ROLE OF AMA IN PATHOGENESIS OF ULCERATIVE COLITIS AND ITS MANAGEMENT

Dr. Gawande Sachin*, Dr. Kamble Sandeep and Dr. Pathan Arshad Khan Rasulkhan

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Abstract

Ulcerative colitis (UC) is a type of Inflammatory Bowel Disease (IBD), characterized by immune-mediated chronic recurrent inflammation of intestinal mucosa that usually involves rectum and may extent proximally to involve all the colonic segments. In UC there is an abnormal activation followed by lack of suppression of immune response to luminal contents, leading to chronic inflammation. In Ayurveda, Ama considered as toxin, resulting from improper digestion of food is considered as the root cause of all the diseases. Bad habits of eating along with other factors leads to Impaired digestive fire i.e. Agni leading to formation of Ama. This Ama being toxin, activates immune reaction initiating pathogenesis of Ulcerative colitis. Getting rid of Ama by treating and preventing its further formation breaks the pathogenesis of the ulcerative colitis and further progression of inflammatory process.

Keywords: Ulcerative colitis, Inflamatory Bowel Disease, Ama, Agni, Ama pachana, Nidan parivarjan.