Abstract

SQUAMOUS CELL CARCINOMA – OVERVIEW

Tanishka Jain*, Shahnawaz Khan, Aditya Pant and B. S. Sonigara

.

Abstract

Squamous cell carcinoma (SCC) is 2 nd most common skin cancer in the world. It occurs mostly in anatomical locations like the head, chest, belly area, pelvis, and front and back of the body. Cutaneous squamous cell carcinoma (CSCC) damage is caused by sun exposure, which is known as actinic keratoses. Actinic means sun rays, and keratoses means roughly scaly skin patches on the skin. They cause serious harm in some cases, but they don’t spread very quickly. Actinic keratoses are mostly caused by factors like scars, chronic radiation, and heat on the mucosal surface. Squamous cell carcinoma (SCC) is a type of nonmelanoma skin cancer that is common in Europe and Asia and is referred to as Caucasian. Factors that can increase the risk of squamous cell carcinoma (SCC) are excessive sun exposure, fair skin, sunburn, exposure to radiation. Therapies used to cure squamous cell carcinoma (SCC) head and neck are locally advanced (AV) and include surgical methods, that are radiotherapy (RT) and concurrent chemotherapy (CT). Radiotherapy (RT) and concurrent chemotherapy (CT). Radiotherapy is one of the most advanced and highly precise techniques used for the treatment of tumors. Studies for Squamous cell carcinoma head and neck, antibodies like cetuximab combined with platinum-based concurrent chemotherapy. Cetuximab is an antibody that targets and binds to epidermal growth factor receptor (EGFR) to inhibit the growth of tumor cells.

Keywords: Anatomic location, Cutaneous squamous cell carcinoma (SCC), Actinic keratoses, Nonmelanoma skin cancer, Caucasians, Locally advanced, Radiotherapy (RT), Concurrent chemotherapy (CT), Cetuximab, Epidermal growth factor receptors.