Abstract

RESEARCH ON: FORMULATION AND EVALUATION OF HERBAL OINTMENT

*Priyanka Deepak Jiwane, Rutuja D. Sonone, Chaitali G. Gayaki Prof. Vishnudas K. Lokhande and Dr. R. S. Bijwar

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Abstract

Azadirachta indica (A. Juss), also known as the neem tree, has been used for millennia as a traditional remedy for a multitude of human ailments. A. indica as an antimicrobial, additional studies are clearly needed to determine the specific mechanisms of action, clinical efficacy, and in vivo safety of neem as a treatment for human pathogens of interest. Herbal ointment for wound healing, integrating extracts from Neem and Aloevera. Physicochemical parameters, including pH, viscosity, and spreadability, were evaluated alongside stability assessments to ensure formulation quality. Neem in herbal formulations for wound management, providing a foundation for further investigation, including in vivo studies to validate efficacy and safety. An ointment is a viscous semisolid preparation used topically on a variety of body surfaces. It’s to formulate and evaluate the antimicrobial herbal ointment from local medicinal plants. The ointment base was prepared and formulation of ointment was done by incorporating the active ingredients in most effective ratio in the base by trituration. After the completion of the formulation, quality of the ointment was assessed in terms of irritancy, spreadability, diffusion and stability Herbal ointment containing Aloe vera, Neem was formulated and evaluated to study antibacterial and antifungal activity. Aloe ointment is exhibiting broad-spectrum antifungal activity against A. varies and antibacterial activity against E.coli. Also it was found that ointment containing mixture of Aloe vera, Neem, showed prominent antifungal activity than antibacterial activity. This ointment can be used in the treatment of sun burns, rashes, burns, wounds and other skin infections. In addition to several dose forms, herbal drugs can also be made as an ointment. On the variability of body exteriors, a cream glutinous semisolid mixture is applied topically. The base was triturated to include the active ingredients in the majority of the effective ratio, completing the preparation of the ointment.

Keywords: Azadirachta indica, Aloe vera, Neem, Herbal ointment, Anti- inflammation, skin