Abstract

FORMULATION AND EVALUATION OF HERBAL ANTIBACTERIAL CREAM FROM SOLANUM XANTHOCARPUM EXTRACT

Shubham Varule, Tanvi Warale* and Samruddhi Warale

.

Abstract

Herbal formulations have gained popularity due to their efficacy, minimal side effects, and eco-friendly nature. This study focuses on the formulation and evaluation of an antibacterial cream containing Solanum xanthocarpum methanolic extract. The plant is known for its potent antibacterial properties, which make it an excellent candidate for topical applications. The cream was formulated using natural ingredients, and its physicochemical properties, stability, and antibacterial efficacy were assessed. The antibacterial screening was conducted against Staphylococcus aureus and Escherichia coli to evaluate its effectiveness. The results indicated that the cream exhibited significant antibacterial activity, making it a promising natural alternative for antibacterial applications.[1] Herbal creams have antibacterial activity because they contain plants with antimicrobial properties. These creams can treat infected skin. How herbal creams work : 1) Damage cell membranes: Herbs can damage the cell walls and membranes of bacteria. 2) Inhibit protein and nucleic acid synthesis: Herbs can inhibit the synthesis of proteins and nucleic acids in bacteria. 3) Increase osmotic pressure: Herbs can increase the osmotic pressure inside bacteria.[2]

Keywords: Solanum Xanthocarpum, Antibacterial, Antioxidant, Antifungal, Antimicrobial, Natural Cream.