Abstract

PHYTOCHEMICAL PROFILING AND THERAPEUTIC RELEVANCE OF VASA LEAF (ADHATODA VASICA): A HOLISTIC VIEW OF AYURVEDA TO MODERN

Dr. Adithya Anil*, Dr. Sntosh Y. M., Dr. Raj Joshi, Dr. Sreechand S. R. and Dr. Umali Mali

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Abstract

Vasa (adathoda vasica) is a well-known medicinal plant widely used in Ayurvedic medicine. It is especially valued for its therapeutic efficacy in treating respiratory conditions and controlling bleeding disorders. This study evaluates the phytochemical profiling, pharmacological activities, and traditional applications of Adathoda vasica leaves. Materials and Methods: Physicochemical analysis was conducted using 30 g of Adathoda leaves. Phytochemical screening of both water and alcohol extracts, a test for glycosides, and thin-layer chromatography were analyzed, adhering to the Ayurvedic pharmacopeia of India. This screening revealed the presence of carbohydrates, flavonoids, tannins, cardiac glycosides, monosaccharides, reducing sugars, and steroids. Thin-layer chromatography substantiated the chemical complexity and variety of phytoconstituents in the sample. Result: The study explored the medicinal properties of Vasa (Adhatoda vasica), highlighting its antimicrobial, anti-inflammatory, antitussive, and hemostatic actions, as supported by various in vivo and in vitro experimental studies. Furthermore, its traditional use in managing respiratory disorders (Shwasa-Kasa), bleeding disorders (Raktapitta), and skin diseases (Tvak Roga) as described in classical Ayurvedic texts was validated. Discussion: Despite the presence of potent alkaloids like vasicine and vasicinone in Adhatoda vasica, the plant has been reported to be relatively safe within therapeutic doses. Its broad pharmacological activities, including Shwasa-Kasa hara (anti-tussive), Raktapitta hara (haemostatic), and Shothahara (anti-inflammatory) properties, support its traditional use in Ayurveda. These effects are in line with its classical indications for respiratory disorders, bleeding conditions, and skin ailments. Conclusion: This research underscores the potential of Vasa (Adhatoda vasica) as a valuable candidate for integrative medicine, with a well-established foundation in Ayurveda texts and substantial modern pharmacological validation. However, future studies focusing on clinical efficacy, pharmacokinetics, and comprehensive toxicological evaluations are essential to confirm its safety and therapeutic applicability in evidence-based practice.

Keywords: Adhatoda vasica, Vasa, Ayurveda, Raktapitta.