Abstract

FORMULATION & EVALUATION OF GUMMIES FROM MULBERRY LEAF EXTRACT

Ishita Patel and *Bijal Patel

Abstract

The increasing demand for patient-friendly dosage forms has accelerated the development of functional gummies as an alternative to conventional tablets and capsules. In the present study, herbal gummies were formulated using mulberry (Morus alba) leaf extract, known for its rich phytoconstituent profile and potent antioxidant, antihyperglycemic, and lipid-lowering activities. Orange flavoring was incorporated to enhance palatability. Batch 6 was identified as the optimized formulation based on key physicochemical evaluations. The optimized gummies demonstrated acceptable weight variation (6.91 g), suitable hardness (11 units), uniform thickness (5 mm) and diameter (17 mm), minimal friability (0.2%), and acceptable moisture loss (5.6%). The pH value (3.04) was favorable for the stability of the herbal actives, and dissolution was achieved within 14 minutes, ensuring prompt release. The formulation maintained the integrity of bioactive compounds, offering a promising alternative delivery system for mulberry leaf phytoconstituents. This study highlights the potential of herbal gummies as an innovative, consumer-friendly dosage form for natural therapeutics, promoting better compliance and enhancing the appeal of herbal medications. Further studies focusing on stability, sensory evaluation, and clinical efficacy are recommended to establish large-scale production and commercialization.

Keywords: Mulberry leaf extract, HM Pectin.