Abstract

PREPARATION AND EVALUATION OF DIFFERENT FORMULATIONS BY USING IVY GOURD LEAF EXTRACT

Mahankali Rajitha*, Gonepally Vaishnavi, Sadula Kiranmai, Daripelly Rohitha, Veerla Tejasri, Sangani Madhulatha, Pasaragonda Soumya, Podduturi Sathish

Abstract

The present study focuses on the extraction and formulation of herbal cosmetic and therapeutic products using Coccinia grandis(ivy gourd) leaves. The leaves were subjected to Soxhlet extraction using methanol as the solvent to obtain a phytochemical-rich extract. This extract, known for its antioxidant, antimicrobial property was then incorporated into various topical formulations, including a cream, ointment and face serum. Each formulation was prepared with suitable excipients and evaluated for phytochemical tests and physicochemical parameters like colour, odour, texture, washability, spread ability, viscosity, and pH. The phytochemical screening has shown the presence of Alkaloids, flavonoids and glycosides. The physicochemical evaluation of the developed formulations has shown pale green colour, Aromatic odour, smooth texture, easy washability, good spread ability and almost neutral pH with no lumps were observed. And additionally, the antimicrobial activity of the ivy gourd extract was assessed through a Minimum Inhibitory Concentration (MIC) test against selected bacterial strain Staphylococcus. The results demonstrated significant antimicrobial potential, suggesting the extract’s suitability for topical applications in skincare. This study highlights the potential of Coccinia grandis leaf extract as a natural and effective ingredient in herbal cosmetic formulations. The promising results of the evaluation tests and MIC assay supports its further development in the cosmetic and pharmaceutical industries. The use of plant-based bioactives provides a sustainable and skin-friendly alternative to synthetic ingredients.

Keywords: Ivy gourd leaf, Soxhlet extraction, anti-microbial, antioxidant, Cream, Ointment, Face serum.