Abstract

CURRENT TRENDS AND FUTURE DIRECTIONS IN OVARIAN CANCER RESEARCH AND TREATMENT

Mansi Thakur*, Bhartendu Sharma*, Ravinesh Mishra, Sheetal Sharma, Jyotsna Bharti and Vasundhara

Abstract

In 2018, the United States is expected to see 22,240 new diagnoses of ovarian cancer and 14,070 deaths due to the disease. The primary reason of gynecological death from cancer is ovarian cancer. The most dangerous gynecologic cancer is EOC (Epithelial ovarian cancer). Globally, 150,000 women will pass suddenly and 230,000 will receive a diagnosis each year. Main signs of ovarian cancer are Heavy periods, vaginal discharge, fatigue. abdominal nausea, excessive hunger, bloating, or abdominal distension, change in bowel function, urinary symptoms, back pain, exhaustion, and weight loss are some of the nonspecific symptoms of EOC that usually appear months before a diagnosis. In advanced EOC, primary debulking surgery (PDS) followed by chemotherapy has been the norm since the 1980s, even though there aren't any upfront randomized trials indicating its true benefits. The various cancer types' treatment approaches vary according to their pathological phases. Promising and successful treatment options will be made possible by early detection.

Keywords: Ovarian Cancer, gynecologic, chemotherapeutic, EOC, fatigue.