Abstract

A REVIEW ARTICLE ON NOVET DRUG DELIVERY SYSTEM

Sandeep Kangani*, C. L. uulu Mayakuntla, Manoi Maram, Bala Chmwiaiah Madduru, Bharath Rflkly Lakki Feddy

Abstract

Drug delivery is the rretbod or procms of administefirig a phaniuceutical corrgourxl to achieve a therapeutic effect in humors or arimits. Ford treatment of human diseases, nasal ard pulmonary rules of drug delivery are gairiig ircreasirg irrportarce. These routes pmvide promising alternatives to parerteral drug delivery particutady for pepñde ard protein therapeutics. For this puqx›sq several drug delivery systerrc have been formulated ard are beirg iriresfigated for nasal ard pulrrorary delivery. These include liposorres, prolijxisorres, rnicrospheres, gels, p drugs, ard cyclodextrirs, armrg others. Nareparticles corrtxised of biodegradable polymers stew assurance in fulfillujg the strirgert requi rreris placed on these delivery systems, such as ability to be trarsfened into an aemsol, stability against forces generated dufing aerosolizatiort biocorripatibility, targeting of specific sites or cell populations in th lung, release of tie drug in a pnxleteméned rranrer, ard degndation within an acceptable penod of the.

Keywords: Targeted Drug Delivery, Micmspheres, Narepaiticles, Lijx›sorres, Niosorres, Ernulsiors, phytosorim.