Abstract

LITERARY, ANALYTICAL AND OBSERVATIONAL CLINICAL EVALUATION OF 500 MG DC-24 CAPSULE, IN DIABETES MELLITUS (MADHUMEHA)

Dr. Ravi Raj*, Dr. Pramod Bhardwaj and Dr. Naveen Aggarwal

Abstract

Diabetes Mellitus has been acknowledged as a major health concern since ancient times, impacting people across different cultures and civilizations. It is a multifaceted metabolic condition marked by consistently high blood sugar levels due to insufficient insulin production, insulin resistance, or a combination of both. In recent years, the global incidence of diabetes has surged, largely because of sedentary behavior and poor eating habits. In Ayurveda, this disorder is closely related to "Madhumeha," a variant of "Prameha," which is attributed to the imbalance of Kapha dosha, derangement of Medo dhatu (fat metabolism), and weakened digestive fire (Agni). These disruptions hinder normal metabolic functions and contribute to the onset and progression of the disease. Interpreting Madhumeha through Ayurvedic principles provides a comprehensive and holistic approach to its prevention and treatment. As per the latest figures from the International Diabetes Federation (IDF), around 72.9 million people in India are currently affected by Diabetes Mellitus. Ayurvedic classics describe this condition as Madhumeha, a type of Vataja Prameha, where the patient passes urine that is sweet in taste. This long-standing metabolic disorder stems from doshic imbalances—especially Vata—as well as Medo dhatu irregularities and impaired Agni, mirroring the characteristics of type 2 Diabetes Mellitus in modern medicine. A clinical study was conducted on 130 individuals who came in with common symptoms such as persistent body aches, a sweet taste in the mouth, burning sensation in the feet, excessive hunger and thirst, frequent urination, and heightened mental stress. Based on detailed clinical evaluation, physical examination, and laboratory investigations, all participants were diagnosed with Madhumeha—known in modern medicine as Type 2 Diabetes Mellitus. In Ayurveda, this condition falls under the broader category of Prameha, a chronic metabolic disorder. To manage the condition, each patient was administered DC-24 Capsules (500 mg), twice daily—once before breakfast and once before dinner—alongside personalized dietary guidance and recommended lifestyle changes. Regular follow-up assessments were carried out every 7 days over a span of 60 days. By the end of the first month, patients began showing noticeable improvements in their symptoms and overall health. These positive changes continued throughout the study duration, indicating that the integrative treatment approach—herbal supplementation combined with diet and lifestyle management—was effective. Overall, the administration of a daily dose of two capsules of DC-24 (500 mg twice a day) led to a statistically significant improvement in blood sugar control (P < 0.005), underscoring the potential of Ayurvedic interventions in managing Type 2 Diabetes Mellitus naturally and holistically.

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