Abstract

PREPARATION AND PERFORMANCE ASSESSMENT OF VAPOR RUB

Deshika Karunanithi*, Durga Chellan, Bharathi Mohan, Senthilkumar Krishna, Kannabirran Vaikumdam

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Abstract

This study presents a chemically formulated topical ointment for alleviating cold and cough symptoms, utilizing a petrolatum–mineral oil base into which Camphor, Menthol, and Eucalyptus oil are homogeneously incorporated as primary cough suppressants and topical analgesics. Gently heating the base ensures even dispersion of these active ingredients, followed by the addition of a minimal, laboratory-grade Thymol fraction to confer mild antimicrobial support without herbal extracts. Upon cooling and packaging under hygienic conditions, the resulting ointment displays a smooth, consistent texture and a characteristic menthol–camphor aroma. When compared to marketed Vaporub formulations, the prepared product offers a similar sensory profile and therapeutic action but incorporates a controlled synthetic composition with a precise Thymol content, avoiding potential variability associated with plant-derived constituents. Additionally, stability testing indicates that the formulated Vaporub maintains its physical consistency, skin-compatible pH, and mild antimicrobial efficacy over time, suggesting it is an effective, well-tolerated alternative for over-the-counter topical relief of cough and nasal congestion.

Keywords: Vaporub, Menthol, Camphor, Petrolatum jelly, Topical Decongestant.