Abstract

A NOVEL DRUG DELIVERY SYSTEM BASED ON PHYTOSOMES - A REVIEW

Rifat Parveen*, Mahima Trivedi, Dr. Ritesh Jain

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Abstract

Phytosomes represent an advanced technology for improving the bioavailability and therapeutic efficacy of plant-derived compounds. This thesis focuses on the systematic preparation of phytosomes and their comprehensive evaluation. The study includes optimization of formulation parameters, physicochemical characterization, and pharmacological assessment of phytosomes, emphasizing their potential in drug delivery systems. Phytosomes have emerged as a transformative platform in drug delivery, designed to overcome the challenges of poor solubility and limited bioavailability often associated with plant-based therapeutics. This review provides a comprehensive overview of phytosome technology, highlighting its structure, benefits, formulation techniques, and therapeutic applications. Through complexation with phospholipids, phytosomes enhance the absorption and stability of phytochemicals, offering a promising solution to improve the efficacy and safety of natural medicines. The paper also outlines recent research advancements, challenges, and future directions for integrating phytosomes into modern pharmaceutical systems. Phytosomes offer a promising approach in cancer treatment by enhancing the bioavailability and efficacy of plant-based compounds. Their ability to improve drug delivery and reduce toxicity makes them a valuable tool in modern oncology. However, challenges such as formulation stability, standardization, and limited clinical data remain.

Keywords: Phytosomes; Phospholipids; Nanocarriers; Phytoconstituents; Bioavailability; Pharmacokinetics; Drug delivery.