Abstract

CONVERGENCE OF AI, NANOTECHNOLOGY, AND SMART POLYMERS: REDEFINING THE FUTURE OF BIOMEDICAL ENGINEERING

Pranjal Tiwari, Ranu Bajpai, Piyush Shakya, Aditya, Anuj Yadav, *Mahendra Sharma

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Abstract

A paradigm shift is occurring in biomedical engineering due to incorporation of artificial intelligence (AI), nanotechnology and smart polymers, three transformative fields that hold the potential to transform healthcare. Smart polymers have been traditionally used as versatile platforms in the areas of stimuli-responsive drug delivery, regenerative medicine and the development of biomedical devices whereas nanotechnology allows highly accurate, specific and minimal invasive treatment and diagnosis methods. Growing interest in AI as a predictive, analytical, and decision-support application has made the design, optimization, and translation of these polymeric nanostructures faster than ever. This review identifies a synergistic interplay between AI, nanotechnology, and smart polymers with an intention to underline the joint capability of this triumvirate to change drug delivery systems, tissue engineering, biosensing, and personalized medicine. Based on the emerging developments, we discuss the case studies oncology, women health, neurodegenerative disorders, infertility, and metabolic diseases to highlight how AI facilitated modeling can be used to design polymer-based nanocarriers and bio-materials in a rational fashion. In addition, we comment on issues of nanotoxicology, bias in data, ethical deployment of AI, and the type of regulatory systems needed to support clinical translation. Lastly, we provide avenues to be investigated in the future, such as artificial intelligence designed polymer based materials, nanotechnology wearable devices, and how quantum computing can be incorporated into the field of biomedical engineering. Together, the intersection between these three frontiers redefines a path forward to Biomedical Engineering 5.0; where intelligence, adaptability, and a patient-centered healthcare is possible.

Keywords: Artificial Intelligence, Nanotechnology, Smart Polymers, Biomedical Engineering, Personalized Medicine, Drug Delivery, Regenerative Medicine.