Abstract

AN OVERVIEW OF REVIEW ARTICLE: DESIGN AND ASSESSMENT OF A NEW RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ETODOLAC AND THIOCOLCHICOSIDE

Vangapandu Prasanna*, Reddy Divya, Dr. K. Rajesh, Mylapalli Ajaykumar, Palagara Vasanth Kumar5, Vinnakota Keerthana

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Abstract

The aim of this work is to develop and validate a simple, sensitive, rapid and accurate and less time consuming validated RP-HPLC method for Etodolac and Thiocolchicoside in pharmaceutical dosage form. The method was developed and validated for various parameters as per ICH guidelines. The results obtained were within the acceptance criteria. The proposed method was applied for the determination of Etodolac and Thiocolchicoside in marketed formulation. The assay results confirm with the label claim of formulation. Hence, the proposed method was found to be satisfactory and could be used for the routine analysis of Etodolac and Thiocolchicoside in combined tablet dosage forms.

Keywords: Dosage forms, Etodolac, RP-HPLC, Thiocolchicoside.