Abstract

CURRENT ADVANCES IN MOEBIUS SYNDROME RESEARCH: EMERGING THERAPIES AND FUTURE DIRECTION

Shreya Shirwadkar*, Neha Pisal, Roshni Verma, Dr. Manasi Kamble

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Abstract

Moebius is a rare condition that affects the facial and eye movement muscles, making it hard for the people to smile, blink or move their eyes side to side. It usually starts from birth and is caused by problems in brain development, involving the facial (VII) and Abducens (VI) cranial nerves. People with MS may also have limb deformities, speech and feeding difficulties, and emotional challenges. The exact cause is not always known, but both genes and environmental factors during early pregnancy may play a role. Diagnosis is based on physical signs and confirmed with MRI scans and sometimes genetic testing. Treatment includes surgery (like facial reanimation), speech therapy, and orthopaedic care, depending on the persons need. New research is exploring how AI, early brain training and genetic therapies could improve diagnosis and treatment. With a team-based approach and continued innovation, the outlook for patients with Moebius syndrome is improving.

Keywords: Moebius Syndrome, Facial paralysis, Congenital anomalies, AI in diagnosis, speech therapy, cranial nerves.