Abstract

A REVIEW ON EUCALYPTUS ESSENTIAL OIL IN THE TREATMENT OF CHRONIC ABSTRUCTIVE PULMONARY DISEASES

Honnesh Nh., Shaik Tanzeel Khan*, Chithrashree K., Anushree Shankar Hs., Ranjitha Ht.

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Abstract

1,8 cineol which is also known as eucalyptol is the main component of eucalyptus oil it is commonly known as Nilgiris which can be extracted from Eucalyptus globules which belongs to the family Myrtaceae. Eucalyptol is the organic compound having two isoprenes (2 methyl 1,3 butadiene). In this review we study about the effect of eucalyptol in the treatment of chronic obstructive pulmonary diseases (COPD). As for studies chronic obstructive pulmonary diseases is characterized by the persisting lung inflammation and air flow limitation which is caused due to the inflammatory mediator cytokinin, leukocytes. The mechanism involves in COPD is transforming growth factor which is the key of cytokinin induces the epithelial mesenchymal transition which leads to airwall remoulding (asthma, copd). Researches have been proven that 1,8 cineol decreases the mRna and protein level in epithelial mesenchymal transformation inducing air wall remoulding and there by treats and reduces the versioning of conditions of asthma and COPD.

Keywords: Eucalyptus oil, 1,8 cineol, isoprene, essential oil, antispasmodic, ant mucolytic, anti-inflammatory and bronchodilator.