Abstract

STUDY OF RELATIVE EFFICIENCY OF MAGNETICALLY ACTIVE BRONSTED ACID WITH LEWIS ACID CATALYST FOR QUINOXALINE SYNTHESIS UNDER IDENTICAL ENVIRONMENT

Pankaj V. Patale, Sushil R. Mathapati, Jaishri L. Somawanshi*

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Abstract

A comparative study of catalytic efficiency of magnetically active Bronsted acid (Fe3O4@SiO2-SO3H) and Lewis acid (ZnO/Fe3O4@PNS) has been accomplished for synthesis of quinoxaline. Quinoxalines were synthesized via cyclocondensation of o-phenylene diamine with phenacyl bromide at room temperature in presence of 10 wt.% catalyst. Both the catalyst showed analogous results under identical condition. The magnetically active, solid supported catalyst with Bronsted acid cites or Lewis acid cites offered near about same efficiency for present transformation. The methodology boasts a hassle-free catalyst preparation and separation process, operates under energy-conserving conditions, yields a commendable (96-86%) output of the targeted moieties, and exhibits catalyst recyclability. These appealing features position it as a superior and eco-friendly alternative to traditional methods for synthesizing quinoxalines.

Keywords: Diamine; Phenacyl bromide; Quinoxaline; ZnO/Fe3O4@PNS; Fe3O4@SiO2-SO3H; Room temperature; magnetically active.