Abstract

REVIEW ARTICLE ON” IN SITU GEL FOR CYTOMEGALOVIRUS FOR OCULAR DELIVERY"

*Mr. P. Pramod Sangam, Dr. R. Yogananda, Chethan Patil DN, Sujay Yadav DK, S. Varun Shankar

.

Abstract

1.1. Overview of in situ gel and Cytomegalovirus (CMV) Infections and Ocular Delivery Challenges In situ gel delivery systems have become popular in pharmacy for providing continuous drug delivery without compromising visual clarity. These systems improve bioavailability, penetration, duration, and medication effectiveness compared to ointments. There are three main types: thermally triggered, pHtriggered, and ionic-strength-triggered systems. Temperaturesensitive hydrogels are commonly used, as they can gel at physiological temperatures, simplifying clinical handling without needing external heat. PH-sensitive gels change in response to surrounding pH, with polymers that either accept or release protons based on the pH.[1]

Keywords: .